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Week 1	Sep 3, 12:00 PM	BIG12|ESPN+	Southeast Missouri State vs Iowa State , L 42-10
Week 2	Sep 10, 5:00 PM	ESPN3	Southeast Missouri State vs Southern Illinois , W 34-31
Week 3	Sep 17, 1:00 PM	ESPN+	Nicholls vs Southeast Missouri State , W 42-16
Week 4	Sep 24, 1:00 PM	ESPN+	Central Arkansas vs Southeast Missouri State , W 35-27
Week 5	Oct 1, 12:00 PM	ESPN+	Southeast Missouri State vs Lindenwood , W 49-28
Week 6	Oct 8, 1:00 PM	ESPN+	Tennessee Tech vs Southeast Missouri State , W 34-20
Week 8	Oct 22, 12:00 PM	ESPN+	Southeast Missouri State vs Northwestern State , W 51-16
Week 9	Oct 29, 12:00 PM	ESPN3	Eastern Kentucky vs Southeast Missouri State , L 28-23
Week 10	Nov 5, 4:00 PM	ESPN3	Southeast Missouri State vs Tennessee State , W 42-0
Week 11	Nov 12, 1:00 PM	ESPN+	Southeast Missouri State vs Eastern Illinois , W 31-7
Week 12	Nov 19, 12:00 PM	ESPN+	Murray State vs Southeast Missouri State , W 52-22
Week 13	Nov 26, 8:00 PM	ESPN2	Southeast Missouri State vs Montana , L 34-24